Undereye Polynucleotides in South London

Undereye Polynucleotides in Streatham & Sydenham

Rejuvenate the delicate eye area with Undereye Polynucleotides in Streatham and Sydenham at Dr Mirali Aesthetics. Polynucleotides are bio-stimulators that encourage skin regeneration, boosting collagen and elastin to improve fine lines, pigmentation/dark circles, hydration and elasticity—ideal for common undereye concerns including mild hollowing. Derived from purified fragments of fish DNA (closely resembling human DNA), they’re a filler-alternative for clients who aren’t suitable for, or prefer not to have, tear trough filler. Your plan is tailored by a GMC-registered doctor with clear aftercare at our trusted South London clinics.

Treatment Snapshot

  • Procedure time: ~20–30 minutes

  • Anaesthetic: Topical numbing as needed

  • Downtime: Low (pin-prick swelling/redness 24–48h)

  • Course: Typically 2–3 sessions spaced 3–4 weeks apart

  • Results: Hydration/comfort in weeks; visible skin-quality improvement builds over 4–8+ weeks

Patient receiving undereye polynucleotide injections at Dr Mirali Aesthetics South London

What are Polynucleotides?

Polynucleotides are bio-polymers (DNA fragments) that act as bio-stimulators, signalling skin cells to repair and remodel. In the undereye, they improve hydration and elasticity, soften fine lines, and brighten the appearance of dark circles. They do not add structural volume like filler, making them a considerate option when puffiness risk or very thin skin makes filler less suitable.

Best for

  • Fine lines/crepiness under the eyes

  • Dark circles/pigmentation appearance

  • Mild hollowing and decreased elasticity

  • Clients seeking a filler-alternative

Benefits

  • Improves dark circles and brightness

  • Softens fine lines; enhances elasticity

  • Hydrates delicate undereye skin

  • Lower risk vs. filler in suitable cases

  • Doctor-led protocol with minimal downtime

Frequently Asked Questions

Procedure

We recommend a course of 3-4 sessions, carried out 3-4 weeks apart for optimal results.
Maintenance session once every 6-9 Months

Duration & Longevity

Time: 45 Mins – 15mins for procedure
Numbing cream is applied to make the procedure comfortable. We use very fine needles to introduce the solution into the skin.

Downtime

Common side effects and swelling and bruising which settle after a few days

Where can I get Undereye Polynucleotides treatment near me?

At our Streatham and Sydenham clinics in South London:

Interested in this treatment

Get in touch today simply by clicking on the button for a free consultation.
Book NowContact us

Our Clinics

Get in touch today simply by clicking on the button for a free consultation.
Sydenham ClinicStreatham Clinic

Our Aesthetic Treatments

At Dr Mirali Aesthetics, we provide a complete range of doctor-led skin and injectable treatments across our Streatham and Sydenham clinics. From anti-wrinkle injections and dermal fillers to skin boosters, mesotherapy and microneedling, explore our services designed to deliver safe, natural and effective results.
Face Mesotherapy treatment at Dr Mirali Aesthetics
Face Mesotherapy

Infuse the skin with vitamins and hydration to restore radiance and smoothness.

Learn more
Dr Mirali Aesthetics Forehead Lines
Forehead Lines

Smooth frown lines for a fresher, more youthful look — with natural results.

Learn more
Patient receiving Obagi Blue Peel Radiance treatment at Dr Mirali Aesthetics South London clinic
Obagi Blue Peel

Instant glow with no peeling, redness, or downtime — perfect before events.

Learn more
Enhance shape, symmetry and hydration with lip filler in Streatham and Sydenham. Doctor-led hyaluronic acid treatment for natural results at our South London clinics.
Lip Fillers

Add shape, volume and hydration for naturally fuller lips.

Learn more
Gummy smile correction in Streatham – Dr Mirali Aesthetics
Gummy Smile Correction

Enhance smile harmony by softening excess gum show.

Learn more
Crow's Feet Lines results at Dr Mirali Aesthetics Streatham
Crow's Feet Lines

Soften eye wrinkles for a brighter, rejuvenated appearance.

Learn more
Frown Line results at Dr Mirali Aesthetics Streatham
Frown Lines

Relax deep frown lines for a smoother, more refreshed appearance.

Learn more

Skin Treatment Insights & Guides

Explore expert advice, treatment benefits and real results from our Streatham and Sydenham aesthetics clinics. From Face Mesotherapy to Microneedling and Profhilo, discover how our doctor-led skin treatments can help you achieve healthy, glowing skin.
Patient receiving Obagi Blue Peel Radiance treatment at Dr Mirali Aesthetics South London clinic
Obagi Blue Peel Radiance vs Other Chemical Peels
Read more
Face Mesotherapy treatment at Dr Mirali Aesthetics
Mesotherapy for Anti-Ageing – Unlock Youthful Skin
Read more
Patient receiving undereye polynucleotide injections at Dr Mirali Aesthetics South London
What Are Undereye Polynucleotides?
Read more

What Our Patients Say

4.9
powered by Google
review us on
Gloria S.
09:05 12 Jul 25
Dr Mirali was very professional informative and friendly . I had Botox with no bruising and very natural effect. I’m very happy with the result . Highly recommend her.
Saeeda C.
19:18 07 Jul 25
My first experience was excellent explanation was brilliant I m really happy looking forward to see again.
Bijal P.
12:08 07 Jul 25
I was recommended to Dr. Mirali through my sister. She was extremely helpful and very friendly. She offered a variety of treatments, and I decided to try polynucleotides. Very reasonable priced and competitive with others. I've noticed a huge difference in the quality of my under eye bags. We did discuss all suitable options, she was very knowledgeable and steered me in the right direction. Would definitely recommend
Louise H.
15:39 05 Jul 25
I went to Dr Mirali when my dentist thought it might help with my jaw pain. I was willing to give it a go because my jaw ached all the time and it was limiting what I could eat. I found Dr Mirali to be calm and professional - she explained the botox procedure clearly. Although the actual injections were quite painful, it was over very quickly. My jaw felt much more comfortable within a few days and I've now been pain-free for 3 months. Botox injections are quite expensive, and I don't know when I'll need more - but I definitely would spend the money with Dr Mirali again. Very happy with the service and the results! 🤩
kajal P.
13:12 09 Jun 25
I had a virtual appointment and face to face appointment with Dr Mirali and she was so welcoming and easy to talk to. She listened to what support I wanted and explained each process, including how to use the products she recommended. Within 2 weeks of being consistent I have already noticed a change to my skin. I would definitely recommend using Dr Mirali and using her simple but effective treatment plan.
Kumari T.
06:21 08 Apr 25
The skin consultation was really good! The way she communicated with both me and my mum was impressive. She did a deep dive into my skin issues and explained how to take care of my skin in a straightforward manner. I appreciated that she focused on a routine instead of jumping straight to chemical peels, which is often what other consultations do. It’s so important for clients to understand the basics first, and I feel like she did a great job at implementing a routine that suits my needs and my mum needs. I’ve always wanted rejuvenated skin but was often confused about the right steps to take. Overall, she really helped simplify things for me And my mum!
Alexandra J.
08:53 07 Mar 25
Dr Mirali is fabulous - had a great consultation ahead of getting masseter botox. I was really keen to book her because of her GP background, and I felt in safe hands the whole way. She took the time to learn about my medical history and background before we even got to the skin/treatment consultation. She was fantastic in the treatment appointment too, answered my many (and usually silly) questions and has stayed in touch to see how the treatment has settled. Would definitely recommend.
Sophia N
10:48 14 Oct 24
Dr Mirali was very knowledgable about my treatment and helped in answering all of my questions both before and after the masseter injections. Thank you!
muna D.
12:05 07 Oct 24
Dr. Mirali has been a godsend. I saw her last winter and again in the summer. She uses a very individual and personalized approach to coming up with a plan for her every client. Her conservative yet effective approach to aesthetics is exactly what I was looking for. She takes a holistic view of treating your skin through a comprehensive regime as well as treatments.She is very thorough and explains every step and every procedure. Her hands very light and as such I did not feel much pain during any of my procedures. She follows up regular and is always available for any question or concerns post treatment. I have recommended Dr. Mirali to my friends and would encourage anyone to book with her. You will mot be sorry.
Dee S
16:57 11 Sep 24
Dr Mirali is fantastic, and takes the time to explain every part of the process in a professional manner. In less than 6 months she has helped to improve the qualify of my skin significantly (I had lots of hyperpigmentation from acne scaring), without damaging the integrity of my skin. She is enthusiastic about what she does and it shows with how much care and effort she puts in. My skin has always been something I was self conscious of without make up, but she’s helped me restore my confidence.